Gulp: Adventures on the Alimentary Canal

THE SAME QUALITY that has allowed Mylar to rival latex as the material of choice for party balloons has secured its place in modern-day flatus research. Mylar is airtight. Your helium-filled Mylar Get Well Soon balloon will continue to float long after you are discharged from the hospital. The Mylar balloon I inflated in 1995 as part of a flatulence study might still, had anyone kept it, contain gas I produced by eating two-thirds of a pound of chili in the Kligerman Regional Digestive Disease Center cafeteria.

Alan Kligerman is the Kligerman of the Kligerman center, and he is the Ak in AkPharma, the company that founded the center and created Beano.* The active ingredient in Beano is an enzyme that breaks down certain complex carbohydrates, called oligosaccharides, found in large quantities in beans and other legumes. You have this enzyme in your colon, courtesy of bacteria that live there. Because your small intestine can’t absorb these complex carbohydrates, they carry on into your colon, where bacteria and their enzymes break them down—and create a lot of hydrogen in the process. Translation: beans make people gassy. Adding Beano to chili while it’s still on the table preempts this. It’s like having a surrogate predigest your beans.

I had visited Kligerman’s lab for a magazine piece. I still have my notes and interview transcripts, and a teal Beano windbreaker* that Kligerman gave me, but the details are hazy. I recall eating my carefully weighed chili at a table with Kligerman and Betty Corson, the voice of the Beano Hotline. My notes attest that a man called Len was also there. My lunch mates were eating the chili too, though they weren’t part of the study. They were just people who like beans, or had come to like them, since AkPharma purchased them in volume and cans could usually be found in the cupboards of the employee kitchen.

“I’ll open up a can of black beans, and I’ll eat the whole can,” said Betty.

Len was nodding. “I’ll take a can of baked beans. Pour the liquid off. That’s what I’ll eat for lunch a lot of times. I hate to admit it, but I’m one of the 50 percent of Americans that’s not troubled by beans.”

When someone at AkPharma says, “Troubled by beans,” trouble doesn’t refer to the embarrassment caused by the sounds or smells of flatulence. (Hydrogen and methane are odorless, remember.) Trouble refers to the pain and discomfort caused by gas inflating your colon. When the colon balloons, it activates stretch receptors that send a message to your brain, which your brain forwards to you as pain. Like most pain, it’s an alarm, a warning system. Because stretching can be a prelude to bursting, your brain is highly motivated to let you know what’s happening down there.

The older you get, the slacker the muscles of your colon become and the more easily the organ balloons. As Len gaily remarked, “We get flabbier all over, inside and out.” Sixty percent of Beano customers, he said, are over fifty-five. People with coronary artery disease whose doctors steer them away from fats and red meat are often advised to incorporate beans into their diet as a replacement protein. “Some of these people,” said Kligerman, “would come back to their doctors, going, ‘I’ll take my chances on a second heart attack over all this gas.’” Cardiologists in the fat-fearing 1980s handed out Beano sample bottles like Halloween candy.

The other food group that troubles the middle-aged gut is dairy. About 75 percent of Asians, African Americans, and Native Americans are deficient in lactase, an enzyme secreted in the small intestine that breaks down lactose, a sugar found in milk products. In Caucasians the rate is around 25 percent. Most can digest milk sugars while they’re young, but they begin to lose the ability as they age. “Once you’re beyond suckling age,” Kligerman pointed out, “there’s no biological reason for you to absorb lactose.” Were it not for the persistent hand of the dairy lobby—Got Marketing?—the notion of grown-ups drinking milk by the glass might seem as odd here as it does in much of the rest of the world.

Milk products follow the same biological plot line as beans. An ornery carbohydrate makes it to the colon intact because the small intestine couldn’t break it down into something absorbable. Colon bacteria go to town on it, spewing clouds of hydrogen in the process. Gastroenterologists can easily diagnose malabsorption of lactose (or gluten, for that matter). In the Bay Area, where I live, people prefer to self-diagnose. And misdiagnose. “Dairy sugar often travels with dairy fat, and big fat loads are hard on the gut,” says gastroenterologist Mike Jones. “People who claim lactose intolerance tend to also voice a belief that they’re gluten-intolerant. Usually with no evidence of either.”

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